Rothenberger K, Pensel J, Hofstetter A, Keiditsch E, Frank F
Lasers Surg Med. 1983;2(3):255-60. doi: 10.1002/lsm.1900020308.
Owing to the biophysical properties involved, the Nd:YAG laser is most suited for coagulation of even inhomogeneous tissue. We determined the optimal laser parameters for therapy of urinary bladder tumors. Deep homogeneous necroses can be obtained without perforation risk of the bladder wall, and the procedure does not cause dangerous damage to the intestinal loops. We have studied animal experiments by close examination and systematic inquiry, and thus we were able to determine sufficient laser parameters in dependence on tissue thickness. Clinical studies verified these results for living human tissue. After some years of clinical use of the Nd:YAG laser we can make the first statistical statements.
由于涉及的生物物理特性，钕：钇铝石榴石激光最适合用于凝固甚至不均匀的组织。我们确定了治疗膀胱肿瘤的最佳激光参数。可以获得深部均匀坏死，而无膀胱壁穿孔风险，并且该手术不会对肠袢造成危险损伤。我们通过仔细检查和系统探究对动物实验进行了研究，从而能够根据组织厚度确定足够的激光参数。临床研究验证了这些针对人体活体组织的结果。在钕：钇铝石榴石激光临床应用数年之后，我们可以做出首批统计学陈述。
