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恶性疾病合并播散性带状疱疹患者的阿昔洛韦治疗

Acyclovir therapy in patients with malignant disease and disseminated herpes zoster.

作者信息

Ackland S P, Bishop J F, Whiteside M G

出版信息

Med J Aust. 1983 Jun 25;1(13):637-8. doi: 10.5694/j.1326-5377.1983.tb136257.x.

DOI:10.5694/j.1326-5377.1983.tb136257.x
PMID:6687918
Abstract

Acyclovir is a new antiviral agent which is active in vitro and in vivo against a variety of herpesviruses. Two cases are reported in which intravenous administration of acyclovir arrested the progress of disseminated herpes zoster within 24 to 48 hours after the beginning of therapy. There was no evidence of toxicity. Thus, acyclovir appears to be useful in the therapy of herpes zoster, but this requires evaluation.

摘要

阿昔洛韦是一种新型抗病毒药物,在体外和体内对多种疱疹病毒均有活性。本文报告了两例病例,在这两例中,静脉注射阿昔洛韦后,在治疗开始后的24至48小时内阻止了播散性带状疱疹的进展。没有毒性证据。因此,阿昔洛韦似乎可用于带状疱疹的治疗,但这需要进一步评估。

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