Parker S W, Stewart A J, Wren M N, Gollow M M, Straton J A
Med J Aust. 1983 Sep 17;2(6):288-90. doi: 10.5694/j.1326-5377.1983.tb122467.x.
The relationship between circumcision and sexually transmissible disease was studied in 1350 men who attended the Public Health Department Special Treatment Clinic in Perth, Western Australia. Evidence of circumcision was obtained by examination. More than 98% of the men studied gave a verbal report of their circumcision status which was consistent with the examination findings. Eight hundred and forty-eight men had STD; 471 men, who presented to the clinic for diagnosis and treatment but who were found not to have STD, constituted the control group. The results of the study show significant associations between the state of being uncircumcised and four major sexually transmissible diseases--herpes genitalis, candidiasis, gonorrhoea and syphilis. Estimates of the relative risk suggest that uncircumcised men are twice as likely as circumcised men to develop herpes genitalis or gonorrhoea, and five times as likely to develop candidiasis or syphilis. However, the data for syphilis should be interpreted with caution because of the small number of cases. No significant increase in risk was found for any of the other sexually transmissible diseases diagnosed at the clinic.
在西澳大利亚州珀斯市公共卫生部特殊治疗诊所就诊的1350名男性中，研究了包皮环切术与性传播疾病之间的关系。通过检查获取包皮环切术的证据。超过98%的研究对象口头报告了他们的包皮环切术状况，这与检查结果一致。848名男性患有性传播疾病；471名到诊所进行诊断和治疗但未被发现患有性传播疾病的男性构成了对照组。研究结果表明，未行包皮环切术与四种主要性传播疾病——生殖器疱疹、念珠菌病、淋病和梅毒之间存在显著关联。相对风险估计表明，未行包皮环切术的男性患生殖器疱疹或淋病的可能性是行包皮环切术男性的两倍，患念珠菌病或梅毒的可能性是其五倍。然而，由于梅毒病例数量较少，梅毒数据的解读应谨慎。在诊所诊断的任何其他性传播疾病中，未发现风险有显著增加。
