Swan G E, Harvey R G
J S Afr Vet Assoc. 1983 Dec;54(4):249-50.
The persistent anthelmintic effect of ivermectin given subcutaneously at 200 mcg/kg was evaluated against induced infections of Haemonchus placei, Ostertagia ostertagi, Cooperia spp. (C. pectinata and C. punctata), Bunostomum phlebotomum and Oesophagostomum radiatum in cattle. Forty-four Friesian bull calves raised under worm-free conditions were restrictively randomized to one untreated control group and 3 ivermectin treated groups of equal size according to mass. Animals in the different treated groups were treated either 9, 7 or 5 d before infestation, which was induced in all animals on the same day. The results are presented as percentage reduction and Non Parametric claims. Nine days after treatment the effect of ivermectin was virtually undiminished against O. ostertagi and B. phlebotomum and 7 d after treatment against Cooperia spp. Counts of all worms were reduced by 99% or more following the treatment given 5 d before infection. According to the Non Parametric Method, "A" claims (i.e. 80% effective in 80% of the treated animals) were achieved against all 5 worms up to 7 d after treatment and against O. ostertagi and B. phlebotomum up to 9 d after treatment.
对皮下注射200微克/千克伊维菌素针对牛体内由捻转血矛线虫、奥斯特他线虫、古柏属线虫（包括辐射食道口线虫和有齿食道口线虫）、牛仰口线虫和辐射食道口线虫引起的感染的持续驱虫效果进行了评估。44头在无蠕虫条件下饲养的弗里斯兰公牛犊根据体重被限制性随机分为一个未处理对照组和3个大小相等的伊维菌素处理组。不同处理组的动物在感染前9天、7天或5天进行处理，所有动物在同一天诱导感染。结果以减少百分比和非参数检验结果呈现。治疗9天后，伊维菌素对奥斯特他线虫和牛仰口线虫的效果几乎没有减弱，治疗7天后对古柏属线虫的效果也几乎没有减弱。在感染前5天进行治疗后，所有蠕虫的数量减少了99%或更多。根据非参数方法，在治疗后7天内对所有5种蠕虫以及在治疗后9天内对奥斯特他线虫和牛仰口线虫均达到了“A”级标准（即在80%的处理动物中有效率达到80%）。
