Williams J C, Sheehan D, Fuselier R H
Am J Vet Res. 1977 Dec;38(12):2037-8.
The efficacy of albendazole in removing gastrointestinal nematodes and tapeworms was studied in 16 treated and 16 untreated (control) beef calves. The anthelmintic was administered as an oral drench at a dose level of 5 ml/45.5 kg of body weight (5 mg/kg). Percentage of efficacy against the various genera was: Trichostrongylus axei, Oesophagostomum radiatum, and Moniezia-100.0; Haemonchus placei, Cooperia spp, and Trichostrongylus colubriformis - greater than 99.0; Ostertagia ostertagi -98.3; and Bunostomum phlebotomum -96.2. Efficacy against Trichuris was 20.2. Efficacy against immature nematodes in the abomasum and small intestine was high, 91.9 and 86.4, respectively, but total numbers of nematodes were not large. Efficacy against immature stages in the cecum and remainder of the large intestine was 48.5. Signs of toxicosis were not observed in calves treated with albendazole.
在16头经过治疗和16头未治疗(对照)的肉牛犊中研究了阿苯达唑驱除胃肠线虫和绦虫的效果。驱虫药以口服灌服的方式给药,剂量为5毫升/45.5千克体重(5毫克/千克)。对各属的驱虫效果百分比为:奥氏类圆线虫、辐射食道口线虫和莫尼茨绦虫——100.0;牛血矛线虫、古柏属线虫和蛇形毛圆线虫——大于99.0;奥斯特他线虫——98.3;和牛钩虫——96.2。对毛首线虫的驱虫效果为20.2。对皱胃和小肠内未成熟线虫的驱虫效果较高,分别为91.9和86.4,但线虫总数不多。对盲肠和大肠其余部分未成熟阶段的驱虫效果为48.5。在用阿苯达唑治疗的牛犊中未观察到中毒迹象。