Constantinou C E, Djurhuus J C, Silverman D E, Towns A B, Wong L, Govan D E
J Urol. 1984 Jan;131(1):86-90. doi: 10.1016/s0022-5347(17)50213-x.
We characterized the isometric pressures generated by the bladder during voluntary detrusor contraction and interruption of flow. Urodynamic studies were done in 34 healthy female volunteers, with a mean age of 29.6 plus or minus 9.3 years. Control urodynamics were done first to characterize bladder and urethral parameters to filling and voiding. Subsequently, isometric detrusor pressures were elicited during bladder filling at increments of 100 ml. by asking subjects to attempt to void against a urethral obstruction produced by an inflated Foley balloon. Isometric pressures also were obtained by interruption of flow through the lumen of the 22F Foley catheter. The results showed that the maximum isometric pressure increase generated remained relatively constant during bladder filling at 39.6 plus or minus 13.1 cm. water. This pressure is not significantly different from voiding pressures developed with a 10F urethral catheter. On the other hand, isometric pressure increases during voiding showed that the increase in bladder pressure following interruption of flow was volume sensitive. The possibility that this volume dependency may result in errors in the interpretation of bladder contractility is discussed.
我们对膀胱在逼尿肌自主收缩及排尿中断期间产生的等长压力进行了特征描述。对34名健康女性志愿者进行了尿动力学研究，她们的平均年龄为29.6±9.3岁。首先进行对照尿动力学检查，以确定膀胱和尿道在充盈及排尿时的参数特征。随后，在膀胱充盈过程中，以100毫升的增量进行等长逼尿肌压力测试，方法是让受试者试图对抗由充气的Foley球囊造成的尿道梗阻进行排尿。还通过中断22F Foley导管管腔内的尿液流动来获取等长压力。结果显示，在膀胱充盈期间，产生的最大等长压力增加相对恒定，为39.6±13.1厘米水柱。该压力与使用10F尿道导管排尿时产生的压力无显著差异。另一方面，排尿期间的等长压力增加表明，排尿中断后膀胱压力的增加对容量敏感。本文讨论了这种容量依赖性可能导致膀胱收缩力解释错误的可能性。
