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[使用马来酸麦角新碱时自发性冠状动脉痉挛的临床、心电图及冠状动脉造影表现的可重复性]

[Reproducibility of the clinical, electrocardiographic and coronarographic aspects of spontaneous coronary spasm with the use of ergonovine maleate].

作者信息

Bramucci E, Specchia G, De Servi S, Angoli L, Mussini A, Marinoni G P, Gavazzi A, Falcone C, Valsecchi O, Montemartini C

出版信息

G Ital Cardiol. 1978 May;8(5):489-95.

PMID:669106
Abstract

Five patients affected by angina pectoris showed a spontaneous attack of myocardial ischemia in the course of coronary arteriography examination. During the ischemic episode it was shown a severe coronary arterial spasm promptly relieved by nitroglycerin. In these patients the administration of ergonovine maleate induced the same clinical, electrocardiographic and coronariographic patterns of spontaneous ischemic episodes. These data support the hypotesis that the ergonovine maleate administration is a suitable test for detection of the vasospastic pathogenesis in acute myocardial ischemia.

摘要

五名患有心绞痛的患者在冠状动脉造影检查过程中出现了自发性心肌缺血发作。在缺血发作期间,显示出严重的冠状动脉痉挛,硝酸甘油可迅速缓解。在这些患者中,给予马来酸麦角新碱可诱发与自发性缺血发作相同的临床、心电图和冠状动脉造影表现。这些数据支持了这样一种假说,即给予马来酸麦角新碱是检测急性心肌缺血中血管痉挛发病机制的合适试验。

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