Specchia G, Angoli L, De Servi S, Mussini A, Bramucci E, Marinoni G, Ray M, Montemartini C, Di Guglielmo L, Bobba L
G Ital Cardiol. 1976;6(7):1177-83.
In 6 patients affected by spontaneous angina with S-T elevation and coronariographic findings of obstruction, intravenous administration of ergonovine maleate determined the same clinical and ECG patterns of spontaneous episodes. The coronary arteriography during pain showed a marked spasm with occlusion of a large coronary vessel in four patients. In 2 patients with atypical chest pain and normal coronariogram, E.M. did not induce pain, ECG abnormality or coronariographic alterations. The role of spasm in spontaneous angina is discussed.
在6例患有自发性ST段抬高型心绞痛且冠状动脉造影显示有阻塞的患者中，静脉注射马来酸麦角新碱后出现了与自发性发作相同的临床和心电图表现。疼痛发作时的冠状动脉造影显示，4例患者出现明显痉挛，伴有一支大冠状动脉血管闭塞。在2例胸痛不典型且冠状动脉造影正常的患者中，马来酸麦角新碱未诱发疼痛、心电图异常或冠状动脉造影改变。文中讨论了痉挛在自发性心绞痛中的作用。
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