Pearlson G D, Garbacz D J, Tompkins R H, Ahn H S, Gutterman D F, Veroff A E, DePaulo J R
Am J Psychiatry. 1984 Feb;141(2):253-6. doi: 10.1176/ajp.141.2.253.
The presence of lateral ventricular enlargement in some manic-depressive subjects, as assessed by ventricular-brain ratios (VBRs), has been reported. A study of 27 bipolar patients and 27 individually matched normal controls confirmed that finding. Bipolar patients had significantly larger VBRs than did controls. Clinical measures associated with the presence of ventricular enlargement in the bipolar patients included more frequent hospitalizations and histories of persistent unemployment. Other measures of illness severity or social deterioration were not significantly associated with large VBR.
据报告，通过脑室 - 脑比率（VBRs）评估，一些躁郁症患者存在侧脑室扩大的情况。一项针对27名双相情感障碍患者和27名个体匹配的正常对照者的研究证实了这一发现。双相情感障碍患者的VBRs显著高于对照组。与双相情感障碍患者脑室扩大相关的临床指标包括更频繁的住院治疗和持续失业史。其他疾病严重程度或社会衰退的指标与较大的VBR并无显著关联。
