Shima S, Shikano T, Kitamura T, Masuda Y, Tsukumo T, Kanba S, Asai M
Acta Psychiatr Scand. 1984 Sep;70(3):275-7. doi: 10.1111/j.1600-0447.1984.tb01208.x.
Compared with controls, 46 depressed patients showed increased ventricular-brain ratio (VBR). Patients with poor outcome, single episode, onset at 50 years or over, or without melancholia were found to have greater VBR than controls.