Keighley M R, Razay G, Fitzgerald M G
Ann R Coll Surg Engl. 1984 Jan;66(1):49-51.
The influence of diabetes on mortality and morbidity following operations for obstructive jaundice has been assessed in 118 consecutive patients, all of whom received antibiotic cover, subcutaneous heparin and intravenous mannitol. 44 patients had diabetes mellitus (37%). There were 12 post operative deaths (10%). Factors which significantly contributed to mortality included; admission values for alkaline phosphatase, creatinine, haematocrit, bilirubin and age of patient over 70 years. Although mortality was not increased in diabetics, wound sepsis was significantly more common (20% and 4% respectively; p less than 0.02). The majority of infections were due to antibiotic sensitive Staphylococcus aureus. Diabetes did not influence survival after operation for malignant disease.
对118例连续性患者进行了评估，以探讨糖尿病对梗阻性黄疸手术后死亡率和发病率的影响。所有患者均接受了抗生素覆盖、皮下肝素和静脉注射甘露醇治疗。44例患者患有糖尿病（37%）。术后有12例死亡（10%）。导致死亡率显著升高的因素包括：碱性磷酸酶、肌酐、血细胞比容、胆红素的入院值以及70岁以上患者的年龄。虽然糖尿病患者的死亡率没有增加，但伤口感染明显更为常见（分别为20%和4%；p<0.02）。大多数感染是由对抗生素敏感的金黄色葡萄球菌引起的。糖尿病并不影响恶性疾病手术后的生存率。
