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宫颈原位癌:子宫切除术后细胞学检查是否值得?

Carcinoma-in-situ of the cervix: is post-hysterectomy cytology worthwhile?

作者信息

Fawdry R D

出版信息

Br J Obstet Gynaecol. 1984 Jan;91(1):67-72. doi: 10.1111/j.1471-0528.1984.tb05281.x.

DOI:10.1111/j.1471-0528.1984.tb05281.x
PMID:6691948
Abstract

The cytological records for the years 1950-1980 from South East Scotland revealed 1062 patients who had had histologically confirmed carcinoma-in-situ (or severe dysplasia) of the cervix at the time of hysterectomy. Ten cases of early 'recurrence' were detected in the first year of follow-up. During 4304 women-years of subsequent regular follow-up by vaginal vault smears, only one further confirmed recurrence was detected, this being a poorly differentiated squamous carcinoma in a 26-year-old patient, 4 years after hysterectomy. Two further patients not in regular follow-up presented clinically with invasive carcinoma. The implications for follow-up policies are discussed.

摘要

1950年至1980年来自苏格兰东南部的细胞学记录显示,1062例患者在子宫切除时经组织学证实患有宫颈原位癌(或重度发育异常)。在随访的第一年发现了10例早期“复发”病例。在随后通过阴道穹窿涂片进行的4304个女性年的定期随访中,仅检测到1例进一步确诊的复发病例,这是一名26岁患者在子宫切除术后4年发生的低分化鳞状癌。另外2例未进行定期随访的患者临床上出现浸润癌。文中讨论了随访策略的意义。

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