Diaz B, Niubo E, Companioni M, Ancheta O, Kouri J
Exp Cell Res. 1984 Feb;150(2):494-8. doi: 10.1016/0014-4827(84)90595-0.
Cytochalasin B (CB) and deoxyglucose alter the electrical responses of the plasma membrane of rat peritoneal macrophages to the presence of phagocytosable latex particles. With both agents, instead of the initial hyperpolarization we previously observed, there is a depolarization. In the case of cytochalasin B (CB) this is followed by a gradual repolarization to the initial resting level, whereas with deoxyglucose the membrane eventually does hyperpolarize. One possible interpretation is that plasma membrane receptors mediate the depolarization in response to phagocytosable particles, but that normally this is masked by other changes effected here by the agents we used.
细胞松弛素B（CB）和脱氧葡萄糖会改变大鼠腹膜巨噬细胞质膜对可吞噬乳胶颗粒存在时的电反应。使用这两种试剂时，并未出现我们之前观察到的初始超极化现象，而是出现了去极化。就细胞松弛素B（CB）而言，随后会逐渐复极化至初始静息水平，而使用脱氧葡萄糖时，膜最终会超极化。一种可能的解释是，质膜受体介导了对可吞噬颗粒的去极化反应，但通常这种反应会被我们所用试剂引起的其他变化所掩盖。
