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与蛋白质S6磷酸化相关的核糖体构象变化。

Ribosome conformational changes associated with protein S6 phosphorylation.

作者信息

Kisilevsky R, Treloar M A, Weiler L

出版信息

J Biol Chem. 1984 Jan 25;259(2):1351-6.

PMID:6693389
Abstract

The relative accessibility of rat liver ribosomal proteins to reductive methylation was examined using ribosomes with unphosphorylated, and extensively phosphorylated S6. Comparison of the results indicated that proteins S3, S4, S7, and S23/24 of the small subunit, and proteins L9, L10, L12, L18, L27, L34, and L36 are involved in a ribosomal conformational change.

摘要

利用含有未磷酸化和高度磷酸化S6的核糖体，研究了大鼠肝脏核糖体蛋白对还原甲基化的相对可及性。结果比较表明，小亚基的S3、S4、S7和S23/24蛋白，以及L9、L10、L12、L18、L27、L34和L36蛋白参与了核糖体构象变化。

相似文献

1
Ribosome conformational changes associated with protein S6 phosphorylation.与蛋白质S6磷酸化相关的核糖体构象变化。
J Biol Chem. 1984 Jan 25;259(2):1351-6.
2
An analysis of alterations in ribosomal conformation using reductive methylation.使用还原甲基化对核糖体构象变化进行的分析。
J Biol Chem. 1978 Oct 10;253(19):7101-8.
3
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Influence of the state of ribosome association on the phosphorylation of ribosomal proteins in isolated ribosome--protein kinase systems from rat cerebral cortex.核糖体结合状态对大鼠大脑皮层分离的核糖体-蛋白激酶系统中核糖体蛋白磷酸化的影响。
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RNA-protein complexes identified by crosslinking of polysomes.通过多核糖体交联鉴定的RNA-蛋白质复合物
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Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'.真核生物核糖体蛋白的分离。60S核糖体亚基蛋白L3、L6、L7'、L8、L10、L15、L17、L18、L19、L23'、L25、L27'、L28、L29、L31、L32、L34、L35、L36、L36'和L37'的纯化与特性分析。
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7
Phosphorylation of ribosomal proteins as a possible control system for protein synthesis. Binding of Met-tRNAf to 40 S ribosomal subunits.核糖体蛋白的磷酸化作为蛋白质合成的一种可能控制系统。甲硫氨酰 - 起始转运核糖核酸与40 S核糖体亚基的结合。
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Mol Biosyst. 2011 Mar;7(3):817-23. doi: 10.1039/c0mb00174k. Epub 2010 Dec 9.

引用本文的文献

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2
Temperature characteristics and adaptive potential of wheat ribosomes.小麦核糖体的温度特性和适应潜力。
Plant Physiol. 1986 Jan;80(1):181-6. doi: 10.1104/pp.80.1.181.
3
Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens.
必需基因中的点突变以及第二个等位基因的缺失或突变：与肿瘤特异性抗原保留的相关性。
J Exp Med. 2001 Aug 6;194(3):285-300. doi: 10.1084/jem.194.3.285.
4
Phorbol ester, serum, and rous sarcoma virus transforming gene product induce similar phosphorylations of ribosomal protein S6.佛波酯、血清和劳氏肉瘤病毒转化基因产物诱导核糖体蛋白S6发生相似的磷酸化。
Proc Natl Acad Sci U S A. 1984 Oct;81(20):6408-12. doi: 10.1073/pnas.81.20.6408.
5
Regulation of a ribosomal protein S6 kinase activity by the Rous sarcoma virus transforming protein, serum, or phorbol ester.劳氏肉瘤病毒转化蛋白、血清或佛波酯对核糖体蛋白S6激酶活性的调节。
Proc Natl Acad Sci U S A. 1985 Nov;82(22):7621-5. doi: 10.1073/pnas.82.22.7621.
6
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