Goldey D H, Mansmann H C, Rasmussen A I
J Am Diet Assoc. 1984 Feb;84(2):157-63.
To assess interrelationships between asthma, corticosteroid therapy, growth, and zinc status in children, measurements of height, zinc and copper in serum and hair, taste acuity, and dietary intakes of energy, protein, zinc,and copper were analyzed for 29 asthmatic, 11 prednisone-treated asthmatic, and 21 non-asthmatic subjects, 6 to 20 years old. Reduced height attainment was significant only for the prednisone-treated asthmatic group and was not correlated with clinical or dietary indexes of zinc status. Dietary intake data were similar for all three groups; in comparison with the RDAs, daily intakes were adequate for both energy and zinc (80% to 90%), high for protein (185% to 225%), and low for copper (35% to 60%). Results confirmed earlier reports of growth retardation in corticosteroid-treated asthmatics; significant indications that reduced food intake or impaired zinc status played a major part were not evident.
为评估儿童哮喘、皮质类固醇治疗、生长及锌状态之间的相互关系，对29名6至20岁的哮喘患儿、11名接受泼尼松治疗的哮喘患儿及21名非哮喘儿童的身高、血清和头发中的锌及铜含量、味觉敏锐度以及能量、蛋白质、锌和铜的膳食摄入量进行了分析。身高增长减缓仅在接受泼尼松治疗的哮喘组中显著，且与锌状态的临床或膳食指标无关。三组的膳食摄入数据相似；与推荐膳食摄入量（RDAs）相比，每日能量和锌摄入量充足（80%至90%），蛋白质摄入量高（185%至225%），铜摄入量低（35%至60%）。结果证实了早期关于皮质类固醇治疗哮喘患儿生长发育迟缓的报道；未发现食物摄入量减少或锌状态受损起主要作用的明显迹象。
