• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种人细小病毒的生化特性

Biochemical characterization of a human parvovirus.

作者信息

Clewley J P

出版信息

J Gen Virol. 1984 Jan;65 ( Pt 1):241-5. doi: 10.1099/0022-1317-65-1-241.

DOI:10.1099/0022-1317-65-1-241
PMID:6693855
Abstract

The buoyant density, nucleic acid, and proteins of the human serum parvovirus-like agent were investigated. Evidence is presented which suggests that the virus has genomic single-stranded DNA, and that complementary strands may be encapsidated in separate virions. Three proteins of 48 000, 68 000 and 80 000 mol. wt. were found to co-purify with viral antigen at a density of 1.43 g/ml on CsCl gradients. On the basis of these properties it is suggested that this virus is a parvovirus.

摘要

对人血清细小病毒样因子的浮力密度、核酸和蛋白质进行了研究。现有证据表明,该病毒具有基因组单链DNA,互补链可能被包裹在不同的病毒粒子中。在CsCl梯度上,发现分子量分别为48000、68000和80000的三种蛋白质与病毒抗原以1.43 g/ml的密度共同纯化。基于这些特性,提示该病毒为细小病毒。

相似文献

1
Biochemical characterization of a human parvovirus.一种人细小病毒的生化特性
J Gen Virol. 1984 Jan;65 ( Pt 1):241-5. doi: 10.1099/0022-1317-65-1-241.
2
The replication of rodent parvovirus X14.
J Gen Virol. 1976 Mar;30(3):337-46. doi: 10.1099/0022-1317-30-3-337.
3
Canine parvovirus: a biochemical and ultrastructural characterization.犬细小病毒:生化与超微结构特征
J Gen Virol. 1982 Sep;62 (Pt 1):113-25. doi: 10.1099/0022-1317-62-1-113.
4
Replication process of the parvovirus H-1. II. Isolation and characterization of H-1 replicative form DNA.细小病毒H-1的复制过程。II. H-1复制型DNA的分离与特性分析。
J Virol. 1974 Feb;13(2):400-10. doi: 10.1128/JVI.13.2.400-410.1974.
5
Parvoviruses.
J Gen Virol. 1973 Jun;20:Suppl:7-15. doi: 10.1099/0022-1317-20-Supplement-7.
6
Characterization of novel populations of MVM virions containing covalent DNA-protein complexes.含有共价DNA-蛋白质复合物的微小病毒(MVM)病毒粒子新群体的特征分析。
Virology. 1989 Jan;168(1):128-37. doi: 10.1016/0042-6822(89)90411-x.
7
Characteristics of feline panleucopaenia virus strains enabling definitive classification as parvoviruses.
Arch Gesamte Virusforsch. 1974;46(3-4):315-24. doi: 10.1007/BF01240073.
8
The terminal protein of minute virus of mice is an 83 kilodalton polypeptide linked to specific forms of double-stranded and single-stranded viral DNA.小鼠微小病毒的末端蛋白是一种与双链和单链病毒DNA的特定形式相连的83千道尔顿多肽。
FEBS Lett. 1988 Dec 19;242(1):22-6. doi: 10.1016/0014-5793(88)80977-3.
9
Structural proteins of parvovirus Lu 3. Evidence for only two protein components within infectious virions.细小病毒Lu 3的结构蛋白。感染性病毒粒子中仅存在两种蛋白质成分的证据。
Arch Gesamte Virusforsch. 1973;43(4):326-33.
10
Biochemical and genomic characterization of muscovy duck parvovirus.番鸭细小病毒的生化与基因组特征
Arch Virol. 1994;139(1-2):121-31. doi: 10.1007/BF01309459.

引用本文的文献

1
Human parvovirus B19 induced apoptotic bodies contain altered self-antigens that are phagocytosed by antigen presenting cells.人细小病毒 B19 诱导的凋亡小体含有被抗原呈递细胞吞噬的自身改变抗原。
PLoS One. 2013 Jun 12;8(6):e67179. doi: 10.1371/journal.pone.0067179. Print 2013.
2
Parvovirus B19V DNA contamination in Chinese plasma and plasma derivatives.中国血浆及血浆衍生物中细小病毒 B19V DNA 的污染。
J Transl Med. 2012 Sep 17;10:194. doi: 10.1186/1479-5876-10-194.
3
Influence of extraction protocol on physical properties of parvovirus B19 DNA.
提取方案对细小病毒 B19 DNA 物理性质的影响。
J Clin Microbiol. 2010 Dec;48(12):4595-7. doi: 10.1128/JCM.00571-10. Epub 2010 Oct 13.
4
Human parvovirus B19.人细小病毒B19
Clin Microbiol Rev. 2002 Jul;15(3):485-505. doi: 10.1128/CMR.15.3.485-505.2002.
5
Extent of sequence variability in a genomic region coding for capsid proteins of B19 parvovirus.编码细小病毒B19衣壳蛋白的基因组区域的序列变异性程度。
Arch Virol. 1995;140(6):1119-25. doi: 10.1007/BF01315420.
6
Direct demonstration of the human parvovirus in erythroid progenitor cells infected in vitro.在体外感染的红系祖细胞中直接证实人细小病毒。
J Clin Invest. 1984 Dec;74(6):2024-32. doi: 10.1172/JCI111625.
7
The human parvovirus. Brief review.人类细小病毒。简要综述。
Arch Virol. 1984;82(3-4):137-48. doi: 10.1007/BF01311158.
8
Identification of the major structural and nonstructural proteins encoded by human parvovirus B19 and mapping of their genes by procaryotic expression of isolated genomic fragments.人细小病毒B19编码的主要结构蛋白和非结构蛋白的鉴定及其基因通过分离基因组片段的原核表达进行定位
J Virol. 1986 Nov;60(2):548-57. doi: 10.1128/JVI.60.2.548-557.1986.
9
Identification and mapping of neutralizing epitopes of human parvovirus B19 by using human antibodies.利用人源抗体鉴定和绘制人细小病毒B19的中和表位
J Virol. 1991 Oct;65(10):5485-90. doi: 10.1128/JVI.65.10.5485-5490.1991.
10
Identification of the region including the epitope for a monoclonal antibody which can neutralize human parvovirus B19.鉴定包含可中和人细小病毒B19的单克隆抗体表位的区域。
J Virol. 1991 Apr;65(4):1667-72. doi: 10.1128/JVI.65.4.1667-1672.1991.