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有限脊髓切开术治疗顽固性癌痛。

Limited myelotomy for the treatment of intractable cancer pain.

作者信息

Gildenberg P L, Hirshberg R M

出版信息

J Neurol Neurosurg Psychiatry. 1984 Jan;47(1):94-6. doi: 10.1136/jnnp.47.1.94.

DOI:10.1136/jnnp.47.1.94
PMID:6693922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1027651/
Abstract

In midline myelotomy a small mechanical or radiofrequency lesion was made at the centre of the spinal cord at a single segment at the thoracolumbar junction or at C1. This procedure was used for the management of cancer pain in 20 patients, in four of whom it was combined with unilateral cordotomy. Of 14 patients with myelotomy alone at the thoracolumbar junction 10 (71.5%) had satisfactory relief of pain, with no complications or untoward side-effects.

摘要

在中线脊髓切开术中,在胸腰段交界处的单个节段或C1水平的脊髓中央制造一个小的机械性或射频性损伤。该手术用于20例癌症疼痛患者的治疗,其中4例患者联合了单侧脊髓切开术。在14例仅在胸腰段交界处行脊髓切开术的患者中,10例(71.5%)疼痛得到满意缓解,且无并发症或不良副作用。

相似文献

1
Limited myelotomy for the treatment of intractable cancer pain.有限脊髓切开术治疗顽固性癌痛。
J Neurol Neurosurg Psychiatry. 1984 Jan;47(1):94-6. doi: 10.1136/jnnp.47.1.94.
2
Limited Midline Myelotomy for Intractable Visceral Pain: Surgical Techniques and Outcomes.局限性中线脊髓切开术治疗难治性内脏痛:手术技术与结果。
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5
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Treatment of medically refractory cancer pain with a combination of intrathecal neuromodulation and neurosurgical ablation: case series and literature review.鞘内神经调节与神经外科消融联合治疗药物难治性癌痛:病例系列及文献综述
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本文引用的文献

1
Fiber size and organization of afferent pathways.传入通路的纤维大小和组织结构。
Arch Neurol. 1961 Aug;5:202-9. doi: 10.1001/archneur.1961.00450140084008.
2
Evoked central nervous system activity relating to peripheral unmyelinated or C fibers in cat.猫中与外周无髓鞘或C纤维相关的诱发中枢神经系统活动。
J Neurophysiol. 1958 Jul;21(4):345-52. doi: 10.1152/jn.1958.21.4.345.
3
[Posterior commissural myelotomy; 107 cases].[后连合脊髓切开术;107例]
Acta Chir Belg. 1953 Jun;52(6):568-74.
4
Commissural myelotomy.连合部脊髓切开术
J Neurosurg. 1969 Nov;31(5):524-7. doi: 10.3171/jns.1969.31.5.0524.
5
Stereotactic cervical myelotomy.立体定向颈髓切断术
J Neurol Neurosurg Psychiatry. 1970 Apr;33(2):224-30. doi: 10.1136/jnnp.33.2.224.
6
Stereotaxic spinal surgery. A preliminary report.立体定向脊柱手术。初步报告。
J Neurosurg. 1969 Oct;31(4):386-92. doi: 10.3171/jns.1969.31.4.0386.
7
Sensations evoked by stimulation in the midbrain of man.
J Neurosurg. 1969 Jan;30(1):14-24. doi: 10.3171/jns.1969.30.1.0014.
8
Multiplicity of subcortical localization of various functions.各种功能的皮质下定位的多样性。
J Nerv Ment Dis. 1968 Jul;147(1):45-8. doi: 10.1097/00005053-196807000-00005.
9
Stereotactic myelotomy.立体定向脊髓切开术。
Proc R Soc Med. 1974 Aug;67(8):771-2. doi: 10.1177/003591577406700840.
10
Stereotaxis of the spinal cord.脊髓的立体定向技术
Confin Neurol. 1972;34(5):299-310. doi: 10.1159/000103073.