Stewart P A, Washburn K W
J Nutr. 1984 Jan;114(1):132-43. doi: 10.1093/jn/114.1.132.
The growth and lipogenic responses of broiler progeny from normal (DwDw male, Dw-female) and dwarf (Dwdw male, Dw-* female) dams to high and low dietary protein were studied. Body weight gains for the DwDw compared to Dwdw male progeny were greater from week 1 to 3, but less from week 7 to 8 and were similar for Dw-* and Dw- females. No significant effects of progeny genotype and no diet X genotype interactions were observed for feed conversion, carcass nitrogen or fat, abdominal fat, growth hormone, triiodothyronine (T3) or thyroxine (T4). Hepatic malic enzyme was elevated in DwDw male progeny compared to Dwdw males, regardless of diet, and was greater in Dw- females than in Dw-* only in response to low dietary protein. Citrate cleavage enzyme was greater in Dw-* than in Dw- females. Low protein resulted in elevated lipogenic enzyme activities, which were more pronounced in progeny of normal dams. A positive relationship observed between malic enzyme activity and T3 levels for all progeny not carrying the dw gene suggests that although circulating levels of thyroid hormones did not differ between genotypes, the cellular response to these hormones was affected by the presence of the dw gene.
研究了正常（DwDw雄性，Dw雌性）和矮小型（Dwdw雄性，Dw - *雌性）母本的肉鸡后代对高、低蛋白日粮的生长和脂肪生成反应。从第1周龄到第3周龄，DwDw雄性后代的体重增加量比Dwdw雄性后代更大，但从第7周龄到第8周龄则较小，Dw - *和Dw - 雌性后代的体重增加量相似。对于饲料转化率、胴体氮或脂肪、腹部脂肪、生长激素、三碘甲状腺原氨酸（T3）或甲状腺素（T4），未观察到后代基因型的显著影响以及日粮×基因型的交互作用。无论日粮如何，DwDw雄性后代的肝脏苹果酸酶活性均高于Dwdw雄性后代，并且仅在低蛋白日粮条件下，Dw - 雌性的肝脏苹果酸酶活性高于Dw - *雌性。Dw - *雌性的柠檬酸裂解酶活性高于Dw - 雌性。低蛋白导致脂肪生成酶活性升高，这在正常母本的后代中更为明显。对于所有未携带dw基因的后代，观察到苹果酸酶活性与T3水平之间存在正相关关系，这表明尽管不同基因型之间甲状腺激素的循环水平没有差异，但dw基因的存在会影响细胞对这些激素的反应。
