Bamberg E
Biophys Struct Mech. 1977 Apr 21;3(1):39-42. doi: 10.1007/BF00536452.
Some basic aspects of incorporation of hydrophobic peptides and proteins in artificial lipid membranes are discussed. As examples valinomycin as a carrier model and gramicidin A as a channel former in lipid vesicles and in planar lipid membranes are presented. In the second part of the lecture some examples of incorporation of membrane proteins into lipid vesicles and planar lipid membranes are reported. The interaction with artificial lipid membranes of the Ca++ ATPase from the sarcoplasmic reticulum, of Rhodopsin, and of Bacteriorhodopsin is presented.
讨论了疏水肽和蛋白质掺入人工脂质膜的一些基本方面。作为例子,介绍了缬氨霉素作为载体模型以及短杆菌肽A作为脂质囊泡和平面脂质膜中的通道形成剂。在讲座的第二部分,报告了一些膜蛋白掺入脂质囊泡和平面脂质膜的例子。介绍了肌质网Ca++ATP酶、视紫红质和细菌视紫红质与人工脂质膜的相互作用。