Miller K A, Zager T D
Mayo Clin Proc. 1984 Jan;59(1):31-4. doi: 10.1016/s0025-6196(12)60339-5.
A survey of 1,008 adolescent girls was performed to characterize adolescent rubella immunity, and susceptibility was defined as a hemagglutination antibody titer of less than 1:8 (the definition used by the Minnesota State Health Department and the pediatric literature). The incidence of rubella susceptibility was 9.1% in the study population and was evenly distributed with regard to current age, age at time of vaccination, and source of vaccination. In subjects with a history of rubella vaccination, 7.4% were susceptible, whereas in the unvaccinated population, the susceptibility rate was 31.7%. Because rubella is a relatively benign disease except when acquired by the fetus during pregnancy, and adolescents are not only approaching the traditional age of motherhood but also experiencing pregnancy in increasing numbers, it is important for physicians to substantiate the rubella susceptibility status of their adolescent female patients.
对1008名青春期女孩进行了一项调查，以了解青春期风疹免疫力的特征，易感性定义为血凝抗体滴度低于1:8（这是明尼苏达州卫生部和儿科文献中使用的定义）。研究人群中风疹易感性的发生率为9.1%，在当前年龄、接种疫苗时的年龄以及疫苗接种来源方面分布均匀。在有风疹疫苗接种史的受试者中，7.4%易感染，而在未接种疫苗的人群中，易感性率为31.7%。由于风疹除了在孕期由胎儿感染外是一种相对良性的疾病，而且青少年不仅正接近传统的生育年龄，而且怀孕的人数也在增加，因此医生确定其青春期女性患者的风疹易感性状况非常重要。
