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硬膜外血肿:迈向零死亡率。一项前瞻性研究。

Extradural hematoma: toward zero mortality. A prospective study.

作者信息

Bricolo A P, Pasut L M

出版信息

Neurosurgery. 1984 Jan;14(1):8-12. doi: 10.1227/00006123-198401000-00003.

Abstract

This is a prospective analysis of 107 consecutive cases of extradural hematoma treated during the last 3 years at the Department of Neurosurgery of the University Hospital of Verona (Italy). The overall mortality was 5%; 89% of the patients made a good recovery or had only moderate residual disability. We regard this as meaningful progress compared to recent reports from other sources showing mortality rates of approximately 20%. The majority of our patients (57%) underwent operation within 6 hours of injury; 60% went into surgery with a Glasgow coma scale (GCS) score between 8 and 15. No deaths occurred among patients reaching surgery with a GCS score of 8 or better; all patients with scores of 8 to 15 made a good recovery (63 cases). Seventeen patients went into surgery while still free of neurological signs, and 8 had only one dilated pupil; all 25 made good recoveries. A flexion posture at admission cuts the chances of a good outcome by one-half; an extension posture cuts the chances to one-fourth. Ninety-five per cent of the patients had fractures of the skull; only 21% had the classical lucid interval. The cause of all 5 deaths was identified as stemming from avoidable errors in management in outlying hospitals (2 cases) or in our own department (3 cases). The results of this study indicate that zero mortality from extradural hematoma is a realistic goal for a modern, well-run care system for head-injured patients that includes prompt referral by community doctors and suitable hospital facilities for constant access to emergency neurosurgery.

摘要

这是一项对意大利维罗纳大学医院神经外科过去3年连续收治的107例硬膜外血肿病例的前瞻性分析。总死亡率为5%;89%的患者恢复良好或仅有中度残疾。与其他来源近期报告显示的约20%的死亡率相比,我们认为这是有意义的进展。我们的大多数患者(57%)在受伤后6小时内接受了手术;60%的患者接受手术时格拉斯哥昏迷量表(GCS)评分在8至15分之间。GCS评分8分或更高的患者手术中无死亡病例;所有评分在8至15分的患者恢复良好(63例)。17例患者在仍无神经体征时接受了手术,8例仅有一侧瞳孔散大;所有25例均恢复良好。入院时呈屈曲姿势会使良好预后的机会减半;呈伸展姿势会使机会降至四分之一。95%的患者有颅骨骨折;只有21%有典型的清醒期。所有5例死亡的原因均被确定为来自偏远医院(2例)或我们自己科室(3例)可避免的管理失误。这项研究的结果表明,对于一个为头部受伤患者提供现代、运作良好的护理系统,包括社区医生的及时转诊和有持续急诊神经外科手术的合适医院设施,硬膜外血肿零死亡率是一个现实目标。

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