Yamada M, Kashiwamura K, Nakamura Y, Ota T, Nakamura K
Folia Psychiatr Neurol Jpn. 1978;32(2):191-7. doi: 10.1111/j.1440-1819.1978.tb00140.x.
Studies were made on the groups of psychiatric symptoms of Neuro-Behçet's syndrome in six cases considered to be brain stem encephalitis, including one case of autopsy. Psychiatric symptoms appeared from one to eight years after neurological symptoms first occurred. This group of psychiatric symptoms can be divided roughly into the early-stage, middle-stage, terminal-stage and episodic groups. The initias-stage symptom group concerns mainly a change in, and regression of, personality, consisting of being childish, shallow, indifferent, careless, rude, slow in action, euphoric, or depressive. The middle-stage symptom group is made up of indifference, forced smiling, forced crying, amnesia, recent memory impairment, and disorder of sleep rhythm. The terminal-stage symptom group comprises the "lock-in" syndrome, which if advanced, will become Apallisches Syndrome. The episodic symptom group is made up of pathologically abnormal experiences such as hallucinations and delusions and symptoms due to a decline in the level of consciousness such as confusion, delirium and twilight state. Dementia hitherto mentioned in Neuro-Behçet's syndrome should be classified as subcortical dementia.
对6例被认为是脑干脑炎的神经白塞综合征患者的精神症状群进行了研究，其中1例进行了尸检。精神症状在神经症状首次出现后的1至8年出现。这组精神症状大致可分为早期、中期、晚期和发作性组。初期症状群主要涉及人格的改变和衰退，包括幼稚、肤浅、冷漠、粗心、粗鲁、行动迟缓、欣快或抑郁。中期症状群由冷漠、强笑、强哭、失忆、近记忆力减退和睡眠节律紊乱组成。晚期症状群包括“闭锁”综合征，病情进展后会发展为阿-斯综合征。发作性症状群由幻觉和妄想等病理性异常体验以及意识水平下降引起的症状如意识模糊、谵妄和朦胧状态组成。神经白塞综合征中迄今提到的痴呆应归类为皮质下痴呆。
