Piade J P, Pelissier J, Georgescu M, Blotman F, Cadilhac J, Simon L
Rev Rhum Mal Osteoartic. 1984 Jan;51(1):7-13.
Thirty patients with active cervico-brachial neuralgia were investigated by detection of the sensory action potential of the nerve, the spinal somaesthetic evoked potential and the cerebral somaesthetic evoked potential. Stimulation is applied to the affected side and symmetrically to the healthy side, at the finger and at the wrist. The digital stimulation recruits a more specific root territory (2nd finger C6-C7, 5th finger C8-T1). These results were compared to those obtained in a population of 14 controls. In cases of active cervico-brachial neuralgia, the spinal somaesthetic evoked potential from digital stimulation (N16) was always abolished in the painful territory; it was also abolished on the pain free side in 75% of cases, while it was present in 96% of the controls. The spinal somaesthetic evoked potential from stimulation of the wrist was only abolished on the painful side in 29% of cases, but the mean amplitude of N13 was reduced. In contrast, the cerebral somaesthetic evoked potential and the sensory action potential of the nerve were only minimally altered. These changes regress after clinical cure. There is a correlation between the severity of the clinical course and the electrophysiological findings. Isolated abolition of the spinal somaesthetic evoked potential from digital stimulation is a constant feature of benign cervico-brachial neuralgia, while abolition of the spinal somaesthetic evoked potential by stimulation of the finger and of the wrist, bilaterally, corresponds to the most severe forms.
对30例活动性颈臂神经痛患者进行了神经感觉动作电位、脊髓体感诱发电位和大脑体感诱发电位检测。在患侧以及对称的健侧手指和手腕处施加刺激。手指刺激募集的是更特定的神经根区域（食指对应C6 - C7，小指对应C8 - T1）。将这些结果与14名对照者的结果进行比较。在活动性颈臂神经痛病例中，手指刺激诱发的脊髓体感诱发电位（N16）在疼痛区域总是消失；在无痛侧，75%的病例中该电位也消失，而在96%的对照者中该电位存在。手腕刺激诱发的脊髓体感诱发电位仅在29%的病例中患侧消失，但N13的平均波幅降低。相比之下，大脑体感诱发电位和神经感觉动作电位仅有轻微改变。这些变化在临床治愈后消退。临床病程的严重程度与电生理结果之间存在相关性。手指刺激诱发的脊髓体感诱发电位单独消失是良性颈臂神经痛的一个恒定特征，而双侧手指和手腕刺激诱发的脊髓体感诱发电位消失则对应最严重的形式。
