Sebastián C, Raya J P, Ortega M, Olalla E, Lemos V, Romero R
Spinal Surgery Unit, Parque San Antonio Clinic, Malaga, Spain.
Eur Spine J. 1997;6(5):316-23. doi: 10.1007/BF01142677.
Somatosensory evoked potentials (SEPs) were used for continuous monitoring of 210 patients during anterior surgery for cervical myeloradiculopathy, to test how effectively they help avoid irreversible neurological damage during surgery. The pathologies differed in severity and were treated by diskectomy or by extended corporectomy using the Senegas technique. Intraoperative SEP changes were recorded in 84 patients (40%); in 13 (6.2%) of these, changes in SEP amplitude and latency were caused by mechanical stress. SEPs revealed transient episodes of regional ischaemia or neurophysiological anomalies during anaesthesia (mainly hypotension) in 27 patients (12.8%). The traces detected incipient and potentially dangerous mechanical pressure on, or metabolic anomalies of, the spinal cord during manipulation and placement procedures of spinal fixation devices. They were particularly sensitive indicators of ischaemia; one of the most common causes of irreversible injury. The traces of 44 patients (21.0%) improved markedly during surgery. There were no false-negatives in this series and, thanks to the fact that SEPs gave immediate warnings of incipient ischaemia to the surgical team, we had no case of irreversible medullary or nerve-root deficit.
体感诱发电位(SEPs)用于在210例颈椎脊髓神经根病前路手术期间进行连续监测,以测试其在手术期间帮助避免不可逆神经损伤的有效性。病变严重程度不同,采用椎间盘切除术或使用塞内加斯技术进行扩大椎体切除术治疗。84例患者(40%)记录到术中SEP变化;其中13例(6.2%)SEP波幅和潜伏期变化是由机械应力引起的。27例患者(12.8%)的SEP显示麻醉期间(主要是低血压)出现局部缺血或神经生理异常的短暂发作。这些监测结果在脊柱固定装置的操作和放置过程中检测到脊髓上早期的、潜在危险的机械压力或代谢异常。它们是缺血的特别敏感指标,缺血是不可逆损伤最常见的原因之一。44例患者(21.0%)的监测结果在手术期间明显改善。该系列中没有假阴性结果,并且由于SEP能向手术团队即时发出早期缺血警报,我们没有出现不可逆的脊髓或神经根缺损病例。