Seminoma of testicle metastatic to thyroid.

A twenty-four-year-old white man is described who presented with seminoma and initially was treated with standard inguinal orchiectomy and radiation therapy for retroperitoneal disease. The case is reported because of the unusual nature of his later recurrence of disease, which was in the right lobe of the thyroid gland. This is a rare site for isolated recurrence, and there is a paucity of reports of metastatic tumor of any type to the thyroid gland. The patient had a complete remission after combined chemotherapy with cyclophosphamide, vinblastine, bleomycin, and cisplatin.