Lithner F, Törnblom N
Acta Med Scand. 1984;215(1):75-9. doi: 10.1111/j.0954-6820.1984.tb04972.x.
A consecutive series of 189 diabetic patients with manifest gangrenous lesions localized to the feet were studied. These patients had 293 gangrenous lesions localized to 5 different areas: toes 58%, interdigital spaces 6%, dorsa of the feet 10%, metatarsal heads 10% and heels 16%. Cardiac decompensation with edema and edema from other causes were the dominant precipitating factors for the gangrenous lesions. Arterial insufficiency alone or together with other precipitating factors was seen considerably less often. Gangrenous lesions localized to the toes were especially common in patients with long duration of diabetes and in men. In women gangrenous lesions localized to the interdigital spaces and to the heels were more common. Multiple gangrenous lesions were more common in patients with cardiac decompensation, while the occurrence of only one lesion was especially common in patients with signs of arterial insufficiency and in men.
对连续的189例足部出现明显坏疽性病变的糖尿病患者进行了研究。这些患者共有293处坏疽性病变,分布于5个不同区域:脚趾58%,趾间间隙6%,足背10%,跖骨头10%,足跟16%。心脏失代偿伴水肿以及其他原因引起的水肿是坏疽性病变的主要诱发因素。单独的动脉供血不足或与其他诱发因素共同作用的情况则少见得多。脚趾部位的坏疽性病变在糖尿病病程较长的患者以及男性中尤为常见。女性中,趾间间隙和足跟部位的坏疽性病变更为常见。多发坏疽性病变在心脏失代偿患者中更为常见,而仅出现一处病变在有动脉供血不足体征的患者以及男性中尤为常见。