Alexander S J, Gilmore R I
Am J Hematol. 1984 Jan;16(1):95-8. doi: 10.1002/ajh.2830160113.
A case of agranulocytosis in an 86-year-old man after 8 weeks treatment with quinidine sulfate is described. Acute phase serum from the patient demonstrated antineutrophil activity by the microgranulocytotoxicity assay. Review of the literature reveals that more than one mechanism could cause this idiosyncratic immune-mediated agranulocytosis.
本文描述了一名86岁男性在接受硫酸奎尼丁治疗8周后发生粒细胞缺乏症的病例。通过微粒细胞毒性试验，患者急性期血清表现出抗中性粒细胞活性。文献回顾显示，多种机制可能导致这种特异质性免疫介导的粒细胞缺乏症。
