Schaap T, Shemer R, Palti Z, Sharon R
Am J Hum Genet. 1984 Jan;36(1):143-51.
An analysis of previous spontaneous abortions and the frequencies of blood-group combinations in mother-child pairs was carried out in 500 gravidae. The rate of previous spontaneous abortions in blood-group-O women whose latest child has blood group B is significantly higher than in all other women. On the other hand, the combination mother B/child AB is rarer than expected, but no increase in the rate of previous spontaneous abortions is obvious among these women. These discrepancies are interpreted as an indication that prenatal selection associated with ABO incompatibility may operate at various stages from fertilization through pregnancy, and that different incompatible combinations may be subject to selection at different stages.
对500名孕妇进行了既往自然流产情况及母婴血型组合频率的分析。最新孩子为B型血的O型血女性既往自然流产率显著高于所有其他女性。另一方面,母亲为B型血/孩子为AB型血的组合比预期少见,但这些女性中既往自然流产率并无明显增加。这些差异被解释为表明与ABO血型不相容相关的产前选择可能在从受精到妊娠的各个阶段起作用,并且不同的不相容组合可能在不同阶段受到选择。