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[刺激下丘脑腹内侧核时家兔丘脑束旁复合体神经元对血管紧张素Ⅱ的敏感性]

[Sensitivity of neurons in the rabbit thalamus parafascicular complex to angiotensin II during stimulation of the ventromedial hypothalamus].

作者信息

Kol'dits M, Kravtsov A N

出版信息

Biull Eksp Biol Med. 1984 Feb;97(2):172-4.

PMID:6696983
Abstract

A study was made of the sensitivity of parafascicular neurons of the thalamus to angiotensin II (A-II) applied microiontophoretically. Almost half of the neurons investigated (48,5%) were discovered to be sensitive to the peptide. Stimulation of the ventromedial hypothalamus provoked marked changes in the pattern of the responses of parafascicular neurons of the thalamus to A-II. The data obtained suggest that the sensitivity of parafascicular neurons of the thalamus, the pattern of responses to biologically active substances may be altered dynamically under the influence of excitations evoked by stimulation of the hypothalamus.

摘要

对丘脑束旁核神经元对微量离子导入法施加的血管紧张素II(A-II)的敏感性进行了一项研究。发现几乎一半被研究的神经元(48.5%)对该肽敏感。刺激下丘脑腹内侧核会引起丘脑束旁核神经元对A-II反应模式的显著变化。所获得的数据表明,在下丘脑刺激所诱发的兴奋影响下,丘脑束旁核神经元的敏感性、对生物活性物质的反应模式可能会动态改变。

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