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Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide.
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Effect of mefloquine on hepatic drug metabolism in the rat: comparative study with primaquine.
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The effects of primaquine stereoisomers and metabolites on drug metabolism in the isolated perfused rat liver and in vitro rat liver microsomes.
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Inhibition of tolbutamide elimination by cimetidine but not ranitidine.
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Effect of enzyme induction and inhibition on the fate of metronidazole and tinidazole in the rat.
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Inhibition of tolbutamide metabolism by substituted imidazole drugs in vivo: evidence for a structure-activity relationship.
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引用本文的文献
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Assessment of the involvement of CYP3A in the vitro metabolism of a new modulator of MDR in cancer chemotherapy, OC144-193, by human liver microsomes.
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Effect of chlormethiazole on hepatic monooxygenases activity in vivo.
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4
Inhibition of tolbutamide metabolism by substituted imidazole drugs in vivo: evidence for a structure-activity relationship.
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5
Lack of inhibition of tolbutamide hydroxylation by cimetidine in man.
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Tolbutamide 4-hydroxylase activity of human liver microsomes: effect of inhibitors.
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7
Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide.
Eur J Clin Pharmacol. 1988;34(2):157-63. doi: 10.1007/BF00614553.
8
In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines.
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Evaluation of hepatic dysfunction in endotoxin pretreated rats using tolbutamide as a marker.
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本文引用的文献
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The fate of antipyrine in man.
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SULPHAPHENAZOLE-INDUCED HYPOGLYCAEMIC ATTACKS IN TOLBUTAMIDE-TREATED DIABETICS.
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The effect of cimetidine on in vitro and in vivo microsomal drug metabolism in the rat.
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Phenobarbitone interaction with oral contraceptive steroids in the rabbit and rat.
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Cimetidine potentiates the anticoagulant effect of warfarin by inhibition of drug metabolism.
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Comparison of the in vivo and in vitro rates of formation of the three main oxidative metabolites of antipyrine in man.
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Prediction of drug-drug interaction from in vitro plasma protein binding and metabolism. A study of tolbutamide-sulfonamide interaction in rats.
Biochem Pharmacol. 1981 Dec 15;30(24):3347-54. doi: 10.1016/0006-2952(81)90611-0.
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Differential effects of enzyme induction on antipyrine metabolite formation.
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Inhibition of drug metabolism by the antimalarial drugs chloroquine and primaquine in the rat.
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Assessment of the drug metabolism capacity of the liver.
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