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链脲佐菌素诱导的糖尿病早期大鼠膀胱的平滑肌

The smooth muscle of rat bladder in the early stages of streptozotocin-induced diabetes.

作者信息

Lincoln J, Haven A J, Sawyer M, Burnstock G

出版信息

Br J Urol. 1984 Feb;56(1):24-30. doi: 10.1111/j.1464-410x.1984.tb07157.x.

DOI:10.1111/j.1464-410x.1984.tb07157.x
PMID:6697101
Abstract

The morphology of the rat bladder was studied following 8 weeks of streptozotocin-induced diabetes, at which stage distension of the bladder had occurred. Evidence is presented for hypertrophy of the smooth muscle of the bladder wall in experimental diabetes. It is suggested that the morphological changes found in the diabetic rat bladder are associated with polyuria. The results are discussed in relation to clinical studies of bladder dysfunction in diabetes mellitus.

摘要

在链脲佐菌素诱导的糖尿病持续8周后,对大鼠膀胱的形态进行了研究,此时膀胱已出现扩张。有证据表明实验性糖尿病中膀胱壁平滑肌肥大。提示糖尿病大鼠膀胱中发现的形态学变化与多尿有关。结合糖尿病膀胱功能障碍的临床研究对结果进行了讨论。

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Connective tissue and its growth factor CTGF distinguish the morphometric and molecular remodeling of the bladder in a model of neurogenic bladder.
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Gender and genetic differences in bladder smooth muscle PPAR mRNA in a porcine model of the metabolic syndrome.代谢综合征猪模型中膀胱平滑肌PPAR mRNA的性别和遗传差异。
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