Axelsson G, Rylander R
Int J Epidemiol. 1984 Mar;13(1):94-8. doi: 10.1093/ije/13.1.94.
A questionnaire on pregnancy outcome was distributed to 782 women engaged in laboratory work at some time between 1968 and 1979. The response rate was 95%. Reported data on miscarriages, malformations and birth weights were compared to data in hospital records and central registers. Twelve per cent of the reported miscarriages could not be verified. Work with solvents was more frequently reported for these miscarriages as compared to those which could be verified or those which were anamnestically recorded. Fifty per cent of the malformations reported in the questionnaires were also found in registers or hospital records. Regarding birth weights, 28% of the infants had different birth weights reported in questionnaires than were found recorded in the Swedish Medical Birth Register. It is suggested that questionnaire data should be completed with information from sources having a higher validity when the influence of environmental factors on pregnancy outcome is studied.
一份关于妊娠结局的问卷被分发给了782名在1968年至1979年期间曾从事实验室工作的女性。回复率为95%。将报告的流产、畸形和出生体重数据与医院记录及中央登记处的数据进行了比较。报告的流产中有12%无法得到证实。与那些能够得到证实的流产或通过回忆记录的流产相比，这些无法证实的流产更频繁地报告与接触溶剂的工作有关。问卷中报告的畸形有50%也在登记处或医院记录中被发现。关于出生体重，问卷中报告的婴儿有28%的出生体重与瑞典医学出生登记处记录的不同。研究环境因素对妊娠结局的影响时，建议用有效性更高的来源信息来完善问卷数据。
