Stern T A, Mulley A G, Thibault G E
JAMA. 1984 Apr 20;251(15):1983-5.
During a four-year period, 255 persons were admitted to a medical intensive care unit 283 times (5% of all admissions) for treatment of drug overdose. Because of the high personal and social costs associated with overdose and the high rate of repeated overdose admissions, we prospectively studied 104 patients who had taken an overdose admitted during a 20-month period to define better the precipitants of overdose and the prognosis after intensive care unit admission for overdose. Of 103 hospital survivors, 88 consented to and could be reached for follow-up (mean duration, ten months). During that time, 8% died (5% by overdose) and 42% had been readmitted for another nonfatal overdose or for psychiatric illness. Prior psychiatric treatment was associated with subsequent readmission; 61% with a history of suicide attempt were readmitted during the follow-up period. Demographic characteristics, psychiatric evaluation, and medical history were not associated with subsequent hospitalization or death from overdose.
在四年期间，255人因药物过量治疗被收治入住医疗重症监护病房283次（占所有入院人数的5%）。由于过量用药带来的高昂个人和社会成本以及重复过量用药入院率很高，我们前瞻性地研究了在20个月期间收治的104例过量用药患者，以更好地确定过量用药的诱发因素以及过量用药入住重症监护病房后的预后情况。在103名医院幸存者中，88人同意并能够接受随访（平均时长为十个月）。在此期间，8%的患者死亡（5%死于过量用药），42%的患者因另一次非致命性过量用药或精神疾病再次入院。先前的精神科治疗与随后的再次入院有关；在随访期间，有自杀未遂史的患者中有61%再次入院。人口统计学特征、精神科评估和病史与随后的住院治疗或过量用药死亡无关。
