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早期手术在急性出血性坏死性胰腺炎(AHNP)治疗中的作用。

The role of early surgery in the treatment of acute hemorrhagic necrotizing pancreatitis (AHNP).

作者信息

Eggink W F, Eeftinck Schattenkerk M, Obertop H, Van der Ven W J, Bruining H A

出版信息

Neth J Surg. 1984 Feb;36(1):6-9.

PMID:6700826
Abstract

A retrospective study of the effect of surgical treatment and the value of different biochemical criteria in the early identification of AHNP in 33 patients with this condition, as proven by laparotomy, is presented. Biochemical criteria were not specific for AHNP and could only infrequently be used for assessment of the severity of acute pancreatitis. Surgical treatment consisted of pancreatic resection in 22 patients and drainage in 11 patients. Twenty-six of the 33 patients died regardless of the type of surgery. Mortality was due to multiple organ failure, either shortly after operation (eight patients) or after a protracted septic clinical course (18 patients). In total AHNP early subtotal pancreatectomy is probably not the treatment of choice since it did not improve the outcome.

摘要

本文呈现了一项回顾性研究,该研究针对33例经剖腹探查证实患有急性坏死性出血性胰腺炎(AHNP)的患者,探讨了手术治疗的效果以及不同生化指标在早期识别AHNP中的价值。生化指标对AHNP并不具有特异性,很少能用于评估急性胰腺炎的严重程度。手术治疗包括22例行胰腺切除术和11例行引流术。33例患者中有26例死亡,无论接受何种手术类型。死亡原因是多器官功能衰竭,其中8例在术后不久死亡,18例在经历漫长的感染性临床病程后死亡。总体而言,AHNP早期行胰腺次全切除术可能并非首选治疗方法,因为它并未改善治疗效果。

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