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早产儿产时胎儿酸中毒:胎儿监测与长期发病率

Intrapartum fetal acidosis in preterm infants: fetal monitoring and long-term morbidity.

作者信息

Westgren M, Hormquist P, Ingemarsson I, Svenningsen N

出版信息

Obstet Gynecol. 1984 Mar;63(3):355-9.

PMID:6700858
Abstract

Fetal heart rate (FHR) and fetal acid-base status were studied prospectively in 61 patients in preterm labor of unknown etiology. Neonatal data were analyzed, and all surviving infants participated in a follow-up study for at least two years. Ominous FHR patterns correlated well with fetal acidosis. Infants with fetal acidosis (pH less than 7.25 in scalp blood) had more neurologic abnormalities in the neonatal period and a higher rate of neurodevelopmental disabilities at the follow-up than nonacidotic infants of the same gestational weeks. In the surveillance of patients in preterm labor electronic fetal monitoring is mandatory. At late or pronounced variable decelerations, pH analysis of fetal scalp blood should be performed immediately. If not available, prompt abdominal delivery is recommended.

摘要

对61例病因不明的早产患者的胎儿心率(FHR)和胎儿酸碱状态进行了前瞻性研究。分析了新生儿数据,所有存活婴儿均参与了至少为期两年的随访研究。不祥的FHR模式与胎儿酸中毒密切相关。与相同孕周的非酸中毒婴儿相比,患有胎儿酸中毒(头皮血pH值低于7.25)的婴儿在新生儿期有更多的神经学异常,且在随访时神经发育障碍的发生率更高。在早产患者的监测中,电子胎儿监护是必需的。出现晚期或明显的可变减速时,应立即进行胎儿头皮血pH分析。若无法进行该分析,建议迅速行剖宫产分娩。

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引用本文的文献

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Doppler studies in the growth retarded fetus and prediction of neonatal necrotising enterocolitis, haemorrhage, and neonatal morbidity.生长受限胎儿的多普勒研究以及新生儿坏死性小肠结肠炎、出血和新生儿发病率的预测。
Br Med J (Clin Res Ed). 1987 Jan 3;294(6563):13-6. doi: 10.1136/bmj.294.6563.13.
2
Perinatal brain damage: predictive value of metabolic acidosis and the Apgar score.围产期脑损伤:代谢性酸中毒和阿氏评分的预测价值。
BMJ. 1988 Jul 2;297(6640):24-7. doi: 10.1136/bmj.297.6640.24.