Wladimiroff J W, Niermeijer M F, Laar J, Jahoda M, Stewart P A
Obstet Gynecol. 1984 Mar;63(3):360-4.
A control group of 165 normal pregnant women between 16 and 22 weeks' gestation was studied by real-time ultrasound scan to establish the normal length of the femur, tibia-fibula complex, humerus, and radius-ulna complex. A group of 32 pregnant women at risk for various types of fetal skeletal dysplasia were studied during the same gestational period. In three cases a structural defect was diagnosed, resulting in elective abortion. Conditions for optimal prenatal diagnosis of skeletal dysplasias are discussed.
对165名妊娠16至22周的正常孕妇组成的对照组进行实时超声扫描，以确定股骨、胫腓骨复合体、肱骨和桡尺骨复合体的正常长度。在同一妊娠期对一组有各种类型胎儿骨骼发育异常风险的32名孕妇进行了研究。其中3例诊断出结构缺陷，导致选择性流产。讨论了骨骼发育异常的最佳产前诊断条件。
