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Xeroderma pigmentosum fibroblasts including cells from XP variants are abnormally sensitive to the mutagenic and cytotoxic action of broad spectrum simulated sunlight.

作者信息

Patton J D, Rowan L A, Mendrala A L, Howell J N, Maher V M, McCormick J J

出版信息

Photochem Photobiol. 1984 Jan;39(1):37-42. doi: 10.1111/j.1751-1097.1984.tb03401.x.

DOI:10.1111/j.1751-1097.1984.tb03401.x
PMID:6701206
Abstract
摘要

相似文献

1
Xeroderma pigmentosum fibroblasts including cells from XP variants are abnormally sensitive to the mutagenic and cytotoxic action of broad spectrum simulated sunlight.
Photochem Photobiol. 1984 Jan;39(1):37-42. doi: 10.1111/j.1751-1097.1984.tb03401.x.
2
Mutagenesis and lethality following S phase irradiation of xeroderma pigmentosum and normal human diploid fibroblasts with ultraviolet light.用紫外线对着色性干皮病和正常人二倍体成纤维细胞进行S期照射后的诱变作用和致死率。
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3
Comparative studies of host-cell reactivation, cellular capacity and enhanced reactivation of herpes simplex virus in normal, xeroderma pigmentosum and Cockayne syndrome fibroblasts.正常、着色性干皮病和科凯恩综合征成纤维细胞中单纯疱疹病毒的宿主细胞复活、细胞能力及增强复活的比较研究
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4
Clinical and photobiological characteristics of Japanese xeroderma pigmentosum variant.日本色素性干皮病变异型的临床和光生物学特征
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5
Abnormal sensitivity of human fibroblasts from xeroderma pigmentosum variants to transformation to anchorage independence by ultraviolet radiation.
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6
Action spectra for inactivation of normal and xeroderma pigmentosum human skin fibroblasts by ultraviolet radiations.紫外线辐射对正常和着色性干皮病人类皮肤成纤维细胞失活的作用光谱。
Photochem Photobiol. 1983 Mar;37(3):307-12. doi: 10.1111/j.1751-1097.1983.tb04478.x.
7
Effect of DNA repair on the cytotoxicity and mutagenicity of polycyclic hydrocarbon derivatives in normal and xeroderma pigmentosum human fibroblasts.DNA修复对正常和着色性干皮病人类成纤维细胞中多环烃衍生物的细胞毒性和诱变性的影响。
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Fluorescent-light-induced lethality and DNA repair in normal and xeroderma pigmentosum fibroblasts.正常及着色性干皮病成纤维细胞中荧光诱导的致死率和DNA修复
Biochim Biophys Acta. 1981 Aug 27;655(1):18-25. doi: 10.1016/0005-2787(81)90061-7.
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Sunlight-induced cancer: some new aspects and implications of the xeroderma pigmentosum model.
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引用本文的文献

1
The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.酿酒酵母REV1的人类同源物的功能是紫外线诱导诱变所必需的。
Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4186-91. doi: 10.1073/pnas.97.8.4186.
2
Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light.着色性干皮病变异型细胞提取物对光产物进行异常且易出错的旁路修复，导致紫外线诱导的突变类型出现极端的链偏向性。
Mol Cell Biol. 1999 Jan;19(1):147-54. doi: 10.1128/MCB.19.1.147.
3
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.
酿酒酵母REV3基因的人类同源基因，该基因编码DNA聚合酶ζ的催化亚基。
Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6876-80. doi: 10.1073/pnas.95.12.6876.
4
Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts.来自突变谱的证据表明，着色性干皮病变异细胞的紫外线高突变性反映了在含有光产物的模板上进行的异常、易出错的复制。
Mol Cell Biol. 1993 Jul;13(7):4276-83. doi: 10.1128/mcb.13.7.4276-4283.1993.
5
Fibroblasts from patients with hereditary cutaneous malignant melanoma are abnormally sensitive to the mutagenic effect of simulated sunlight and 4-nitroquinoline 1-oxide.遗传性皮肤恶性黑色素瘤患者的成纤维细胞对模拟阳光和4-硝基喹啉1-氧化物的诱变作用异常敏感。
Proc Natl Acad Sci U S A. 1984 Feb;81(4):1179-83. doi: 10.1073/pnas.81.4.1179.
6
Thymine dimer repair in fibroblasts of patients with dysplastic naevus syndrome (DNS).发育异常痣综合征（DNS）患者成纤维细胞中的胸腺嘧啶二聚体修复
Experientia. 1988 Feb 15;44(2):169-71. doi: 10.1007/BF01952205.
7
Carcinogens can induce homologous recombination between duplicated chromosomal sequences in mouse L cells.
Mol Cell Biol. 1988 Jan;8(1):196-202. doi: 10.1128/mcb.8.1.196-202.1988.
8
Human DNA repair defects.人类DNA修复缺陷。
J Inherit Metab Dis. 1986;9 Suppl 1:69-84. doi: 10.1007/BF01800860.
9
Effect of nucleotide excision repair in human cells on intrachromosomal homologous recombination induced by UV and 1-nitrosopyrene.
Mol Cell Biol. 1990 Aug;10(8):3945-51. doi: 10.1128/mcb.10.8.3945-3951.1990.
10
Frequency of intrachromosomal homologous recombination induced by UV radiation in normally repairing and excision repair-deficient human cells.紫外线辐射在正常修复和切除修复缺陷的人类细胞中诱导的染色体内同源重组频率。
Proc Natl Acad Sci U S A. 1990 Feb;87(4):1566-70. doi: 10.1073/pnas.87.4.1566.