Whittle I R, Johnston I H, Besser M
J Neurosurg. 1985 Jan;62(1):77-82. doi: 10.3171/jns.1985.62.1.0077.
Continuous intracranial pressure (ICP) monitoring was used to assess 46 children and adolescents in whom a clinical diagnosis of arrested hydrocephalus had been made. Thirty patients (Group A) had previously been treated with cerebrospinal fluid diversion and 16 patients (Group B) had no prior treatment of their hydrocephalus. All patients in Group A either had a confirmed nonfunctioning shunt or had undergone shunt removal. Continuous ICP monitoring showed that 80% of the patients in Group A and 63% of those in Group B had episodic or persistent intracranial hypertension. In four patients (25%) whose initial ICP had been normal or equivocal, repeat ICP monitoring later revealed decompensation or reversal of arrest. When serial psychometric testing demonstrated a fall in cognitive functioning, ICP monitoring revealed abnormal ICP's in 88% of patients. This study shows that many patients with apparent arrest of hydrocephalus in fact have an insidiously progressive disorder. Monitoring of ICP and serial psychometric evaluation are therefore valuable tools in the continuing assessment of arrested hydrocephalus.
采用持续颅内压（ICP）监测对46例临床诊断为脑积水静止期的儿童和青少年进行评估。30例患者（A组）既往接受过脑脊液分流治疗，16例患者（B组）既往未接受过脑积水治疗。A组所有患者均有分流管功能障碍确诊或已接受分流管移除术。持续ICP监测显示，A组80%的患者和B组63%的患者有发作性或持续性颅内高压。4例患者（25%）最初ICP正常或不明确，随后重复ICP监测显示失代偿或静止期逆转。当系列心理测量测试显示认知功能下降时，ICP监测显示88%的患者ICP异常。本研究表明，许多表面上处于脑积水静止期的患者实际上患有隐匿性进行性疾病。因此，ICP监测和系列心理测量评估是持续评估脑积水静止期的有价值工具。
