Dambrain R, Dhem A
Strahlentherapie. 1984 Jan;160(1):39-44.
To understand the changes of the irradiated mandibular bone, we tried to define, in space, how the lesions of the osseous tissue appear and involve. We estimated the vitality of the removed jaw fragments by counting the number of inhabited lacunae (I.L.) and empty lacunae (E.L.) in the sections, without previous decalcification, after surface staining with methylene blue. The results, expressed as percentages of the total amount of osteocytes lacunae, have been compared with the microradiographic aspect of the sections. The most paradoxical finding is that the highest percentages of osteocytes appear in the most destroyed areas. As a conclusion, one may wonder how to proceed to avoid the radiotherapy being followed by attempts for repair: attempts which, indeed, are the source of the complications.
为了解受照射下颌骨的变化，我们试图在空间上确定骨组织病变是如何出现及累及的。我们通过对未经预先脱钙、用亚甲蓝进行表面染色后的切片中存活骨陷窝（I.L.）和空骨陷窝（E.L.）的数量进行计数，来评估切除的颌骨碎片的活力。以骨细胞陷窝总量的百分比表示的结果，已与切片的显微放射照片特征进行了比较。最矛盾的发现是，在破坏最严重的区域出现了最高百分比的骨细胞。总之，人们可能会思考如何在放疗后避免进行修复尝试：而这些尝试实际上正是并发症的根源。
