Derizhanova I S, Reznikova G L
Vopr Onkol. 1984;30(2):19-24.
The paper discusses the results of a study of 22 primary and metastatic carcinoids which occurred in respiratory and digestive tracts with varying degree of differentiation. They formed the basis of the following cytologic criteria for their diagnosis: monomorphism of small cell elements, among which dark and clear ones can be distinguished; small-lumped chromatin pattern in nuclei of clear cells; and teniform and perivascular structures. Diagnosis was verified in all cases by histological and histochemical methods which were complemented by electron microscopy in 3 cases. On the basis of the said characteristics, tumors with endocrine differentiation can be distinguished from other pulmonary and digestive tract neoplasms.
本文讨论了对22例发生于呼吸道和消化道、分化程度各异的原发性和转移性类癌的研究结果。这些结果构成了以下用于诊断的细胞学标准的基础:小细胞成分的单形性,其中可区分出深色和浅色细胞;浅色细胞核中的小块状染色质模式;以及条索状和血管周围结构。所有病例均通过组织学和组织化学方法进行确诊,其中3例辅以电子显微镜检查。基于上述特征,可将具有内分泌分化的肿瘤与其他肺和消化道肿瘤区分开来。