Christensen S B, Ericsson U B, Janzon L, Tibblin S, Trell E
Acta Chir Scand. 1984;150(1):13-9.
A survey of thyroid disease was conducted in 477 middle-aged women selected at random in an urban area where goiter is not endemic. The overall occurrence of thyroid disease was estimated to be 16.2%. Previously known disease was reported by 6.7% of those surveyed, and an additional 9.5% were diagnosed in the present study. The prevalence of all goiter was 11.3%, and of a palpable solitary nodule, 6.5%. Women with goiter were examined by thyroid scintigraphy and fine-needle aspiration cytology. The results of these examinations combined with the conventional clinical examination were considered a sufficient basis for benign diagnosis in all cases except one, a woman with a solitary nodule who was surgically treated because the cytologic report indicated follicular neoplasm; histopathology, however, revealed colloid goiter. The accumulated incidence of hyperthyroidism was 2.3% and of hypothyroidism 0.8%. It is concluded that goiter is a common disorder among women living in non-endemic areas, and that most goiter, including palpable solitary nodules, can be classified after evaluation as multinodular goiter.
在一个并非地方性甲状腺肿流行区的城市，对随机选取的477名中年女性进行了甲状腺疾病调查。甲状腺疾病的总体发生率估计为16.2%。6.7%的受调查者报告有既往已知疾病，另有9.5%是在本研究中被诊断出的。所有甲状腺肿的患病率为11.3%，可触及的孤立性结节患病率为6.5%。对患有甲状腺肿的女性进行了甲状腺闪烁扫描和细针穿刺细胞学检查。除1例因细胞报告提示滤泡性肿瘤而接受手术治疗的孤立性结节女性外，这些检查结果与传统临床检查结果相结合被认为足以作为所有病例良性诊断的充分依据；然而，组织病理学显示为胶样甲状腺肿。甲状腺功能亢进的累积发病率为2.3%，甲状腺功能减退为0.8%。得出的结论是，甲状腺肿在非地方性流行区的女性中是一种常见疾病，并且大多数甲状腺肿，包括可触及的孤立性结节，经评估后可归类为多结节性甲状腺肿。
