Cosio F G, Paylos J, Requena M, Fernández-Yáñez J
Am J Cardiol. 1984 Apr 1;53(8):1018-21. doi: 10.1016/0002-9149(84)90629-5.
Atrial arrhythmias appear to be related to the genesis of intraatrial conduction delays by extrastimuli. To clarify the effects of the basic atrial cycle on intraatrial conduction of extrastimuli, atrial conduction delays and conduction delay zones were measured in 22 patients with and without atrial arrhythmias. Basic cycles were (A) sinus rhythm; (B) paced at the right atrial (RA) appendage with maximum cycle length possible; (C) paced at the RA appendage with cycle length of 600 ms; and (D) paced at the proximal coronary sinus at the same cycle length as B. Extrastimuli were always delivered at the RA appendage. Conduction delays and conduction delay zones were 5- to 7-fold longer when driving stimuli and extrastimuli were delivered through the same electrodes than when the basic cycle was sinus or driven at a distance from the extrastimuli (p less than 0.001). This effect must be considered when groups of patients or the results of interventions are compared.
房性心律失常似乎与额外刺激导致的心房内传导延迟的发生有关。为阐明基础心房周期对额外刺激心房内传导的影响，在22例有或没有房性心律失常的患者中测量了心房传导延迟和传导延迟区。基础周期为：(A)窦性心律；(B)以尽可能长的周期长度在右心房（RA）心耳起搏；(C)以600毫秒的周期长度在RA心耳起搏；以及(D)以与B相同的周期长度在冠状窦近端起搏。额外刺激总是在RA心耳发放。当驱动刺激和额外刺激通过同一电极发放时，传导延迟和传导延迟区比基础周期为窦性或在距额外刺激一定距离处驱动时延长5至7倍（p<0.001）。在比较患者组或干预结果时必须考虑这种效应。
