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伴随肿瘤浸润的良性浆细胞中的核糖体-板层复合体。

Ribosome-lamellae complexes in benign plasma cells accompanying neoplastic infiltrates.

作者信息

Zimmerman K G, Payne C M, Nagle R B

出版信息

Am J Clin Pathol. 1984 Mar;81(3):364-7. doi: 10.1093/ajcp/81.3.364.

DOI:10.1093/ajcp/81.3.364
PMID:6702729
Abstract

Two examples of ribosome-lamellae complexes (RLCs) occurring in benign plasma cells are presented. These were seen utilizing transmission electron microscopy in a case of mycosis fungoides in skin and a fibrosarcoma of a lower extremity. In both cases the accompanying plasmacytic infiltrate was interpreted as reactive and not malignant. Once thought to be a specific marker for hairy cell leukemia, RLCs now have been described in a wide variety of neoplastic diseases (mostly hematologic) and in a few examples of nonneoplastic conditions. RLCs have not been described previously in benign plasma cells. A review of the literature with respect to occurrence and significance of RLCs is presented.

摘要

本文展示了在良性浆细胞中出现的核糖体-板层复合物(RLCs)的两个例子。这些是在皮肤蕈样肉芽肿病例和下肢纤维肉瘤中利用透射电子显微镜观察到的。在这两个病例中,伴随的浆细胞浸润被解释为反应性的而非恶性的。RLCs曾一度被认为是毛细胞白血病的特异性标志物,现在已在多种肿瘤性疾病(主要是血液系统疾病)以及一些非肿瘤性疾病中被描述。此前尚未有关于良性浆细胞中RLCs的报道。本文对RLCs的发生情况及意义进行了文献综述。

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1
Ribosome-lamellae complexes in benign plasma cells accompanying neoplastic infiltrates.伴随肿瘤浸润的良性浆细胞中的核糖体-板层复合体。
Am J Clin Pathol. 1984 Mar;81(3):364-7. doi: 10.1093/ajcp/81.3.364.
2
Ribosome-lamella complex of the lymphocytes in a case of plasmacytic lymphadenopathy with polyclonal hypergammaglobulinemia.一例伴有多克隆高丙种球蛋白血症的浆细胞性淋巴结病中淋巴细胞的核糖体-板层复合体
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Nuclear contour irregularity correlates with Leu-9-, Leu-8- cells in benign lymphoid infiltrates of skin. An ultrastructural morphometric and quantitative immunophenotypic analysis suggesting the normal T-cell counterpart to the malignant mycosis fungoides/Sézary cell.核轮廓不规则与皮肤良性淋巴浸润中的Leu-9、Leu-8细胞相关。一项超微结构形态计量学和定量免疫表型分析提示恶性蕈样肉芽肿/赛塞里细胞的正常T细胞对应物。
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