Zimmerman K G, Payne C M, Nagle R B
Am J Clin Pathol. 1984 Mar;81(3):364-7. doi: 10.1093/ajcp/81.3.364.
Two examples of ribosome-lamellae complexes (RLCs) occurring in benign plasma cells are presented. These were seen utilizing transmission electron microscopy in a case of mycosis fungoides in skin and a fibrosarcoma of a lower extremity. In both cases the accompanying plasmacytic infiltrate was interpreted as reactive and not malignant. Once thought to be a specific marker for hairy cell leukemia, RLCs now have been described in a wide variety of neoplastic diseases (mostly hematologic) and in a few examples of nonneoplastic conditions. RLCs have not been described previously in benign plasma cells. A review of the literature with respect to occurrence and significance of RLCs is presented.
本文展示了在良性浆细胞中出现的核糖体-板层复合物(RLCs)的两个例子。这些是在皮肤蕈样肉芽肿病例和下肢纤维肉瘤中利用透射电子显微镜观察到的。在这两个病例中,伴随的浆细胞浸润被解释为反应性的而非恶性的。RLCs曾一度被认为是毛细胞白血病的特异性标志物,现在已在多种肿瘤性疾病(主要是血液系统疾病)以及一些非肿瘤性疾病中被描述。此前尚未有关于良性浆细胞中RLCs的报道。本文对RLCs的发生情况及意义进行了文献综述。