Hegedüs K, Németh G
Arch Neurol. 1984 Apr;41(4):440-2. doi: 10.1001/archneur.1984.04050160106024.
Seven histologically confirmed cases of intracranial fibromuscular dysplasia (FMD) have been published. A new case of intracranial FMD confined to the basilar artery occurred in a 32-year-old man. The proliferation of fibroblasts and smooth-muscle cells could be observed only in the intima detaching from the media. The neurologic symptoms corresponding to akinetic mutism occurred nine days after pulmonary lobectomy for aspergilloma. We believe that this pure intimal type of FMD consisting of cells without elastic and collagen fibers represents a more undifferentiated and therefore more progressive form of the disease. The FMD can be considered as an overwhelming reaction of so-called pluri-potential smooth-muscle cells of the arterial wall to various stimuli.
已有7例经组织学确诊的颅内纤维肌性发育不良（FMD）病例发表。一名32岁男性发生了一例局限于基底动脉的颅内FMD新病例。仅在内膜与中膜分离处可观察到成纤维细胞和平滑肌细胞的增殖。因曲霉菌瘤行肺叶切除术后九天出现了与运动不能性缄默症相对应的神经症状。我们认为，这种由无弹性和胶原纤维的细胞组成的纯内膜型FMD代表了一种更未分化因而更具进展性的疾病形式。FMD可被视为动脉壁所谓多能平滑肌细胞对各种刺激的一种过度反应。
