Espinosa F, Weir B, Noseworthy T
Can J Neurol Sci. 1984 Feb;11(1):64-8. doi: 10.1017/s0317167100045340.
Cerebral aneurysms are extremely rare in all animals except man. We report the occurrence of a carotid-ophthalmic aneurysm in a cynomolgous monkey two months following accidental occlusion of the ipsilateral cervical internal carotid artery. This was documented angiographically. The aneurysm was deliberately ruptured by the insertion and withdrawal of fine needles. This produced a large subarachnoid hemorrhage visualized on CT scan. There was a progressive severe fall in cerebral blood flow and moderate vasospasm. The neurological status deteriorated on the tenth day and the animal was sacrificed on day 13. On electron microscopy, the aneurysm showed a fibrous wall, and the endothelium showed balloon-like endothelial cells with gaps. Corrugations occurred in the inner aspect of the anterior circulation arteries.
除人类外，脑动脉瘤在所有动物中极为罕见。我们报告了一只食蟹猴在同侧颈内动脉意外闭塞两个月后发生颈内动脉-眼动脉瘤的情况。这通过血管造影记录下来。通过插入和拔出细针故意使动脉瘤破裂。这在CT扫描上显示出大量蛛网膜下腔出血。脑血流量逐渐严重下降，伴有中度血管痉挛。神经状态在第10天恶化，该动物在第13天被处死。电子显微镜检查显示，动脉瘤有纤维壁，内皮有间隙的气球样内皮细胞。前循环动脉内侧出现皱褶。
