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女性患者致密性骨炎与强直性脊柱炎的比较:临床、放射学及人类白细胞抗原分型特征

Comparison of osteitis condensans ilii and ankylosing spondylitis in female patients: clinical, radiological and HLA typing characteristics.

作者信息

de Bosset P, Gordon D A, Smythe H A, Urowitz M B, Koehler B E, Singal D P

出版信息

J Chronic Dis. 1978 Mar;31(3):171-81. doi: 10.1016/0021-9681(78)90032-2.

Abstract

A study comparing 12 patients with ankylosing spondylitis (AS) to 25 with osteitis condensans ilii (OCI), referred to a rheumatic disease center, was carried out to determine whether OCI represents a varient of AS in women. In the group with OCI, chronic lumbodorsal pain was present in 9, 36%, a 'fibrositis' syndrome in 6, 24%, and 16, 64% had recurrent episodes of polyarthralgia. A definite arthritis with effusion developed in 10 patients, 40%. No patient with OCI had iritis or colitis, whereas 4 patients with AS had iritis and four had colitis. Radiographs of the spine showed no evidence of spondylitis in the OCI group. Of the 25 patients with OCI, only 2, 8% were HLA B27 positive compared with 11 of 12 patients with AS, 92%. These results suggest that OCI is not a variant of AS in women.

摘要

一项针对12例强直性脊柱炎(AS)患者和25例致密性骨炎(OCI)患者的研究在一家风湿疾病中心开展,以确定OCI是否为女性AS的一种变体。在OCI组中,9例(36%)存在慢性腰背痛,6例(24%)有“纤维炎”综合征,16例(64%)有复发性多关节痛发作。10例患者(40%)出现了伴有积液的明确关节炎。OCI组中没有患者患有虹膜炎或结肠炎,而4例AS患者患有虹膜炎,4例患有结肠炎。脊柱X光片显示OCI组没有脊柱炎的迹象。在25例OCI患者中,只有2例(8%)HLA B27呈阳性,而12例AS患者中有11例(92%)呈阳性。这些结果表明,OCI不是女性AS的一种变体。

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