Singal D P, de Bosset P, Gordon D A, Smythe H A, Urowitz M B, Koehler B E
J Rheumatol Suppl. 1977;3:105-8.
Using a standard microdroplet lymphocyte cytotoxicity test for tissue typing, the distribution of the HLA antigens was determined in 37 female patients; 25 with osteitis condensans ilii (OCI) and 12 with ankylosing spondylitis (AS). Although low back pain was a common feature of OCI, none of these patients exhibited the limitation of spinal involvement, radiological evidence of spondylitis, or progressive clinical course seen in the AS group. Four of the 25 patients with OCI (16 per cent) were B27 positive vs 11 of the 12 patients with AS (92 per cent). These results suggest that OCI is not a variant of AS in women.
采用标准微量淋巴细胞毒性试验进行组织分型，测定了37例女性患者的HLA抗原分布情况；其中25例为致密性髂骨炎（OCI）患者，12例为强直性脊柱炎（AS）患者。虽然下背痛是OCI的常见特征，但这些患者均未出现脊柱受累受限、脊柱炎的影像学证据或AS组中所见的进行性临床病程。25例OCI患者中有4例（16%）B27呈阳性，而12例AS患者中有11例（92%）B27呈阳性。这些结果表明，OCI不是女性AS的一种变异型。
