Dooley J S, Dick R, George P, Kirk R M, Hobbs K E, Sherlock S
Gastroenterology. 1984 May;86(5 Pt 1):905-9.
Sixty-two patients with bile duct obstruction were referred for the percutaneous transhepatic insertion of an endoprosthesis. This procedure was successful in 53 of the 62 patients. Insertion was possible through 28 of 30 periampullary obstructions, but only through 19 of 26 at the hilum. Eighteen patients suffered complications, but in only 3 cases were these serious, including two procedure-related deaths. Bile duct obstruction was relieved completely in 34 of 46 patients with planned long-term drainage, and was partially relieved in 8 patients. The survival of 40 patients with malignant disease was poor, but none of the 6 patients with benign stricture has died. In 7 of 20 long-term survivors, the endoprosthesis eventually became partially or totally blocked. This technique is an alternative method of relieving itching and jaundice in patients with irresectable tumors or poor operative risk. In patients with benign stricture, the early results are encouraging, but longer follow-up is necessary to evaluate this therapeutic approach.
62例胆管梗阻患者被转诊接受经皮经肝内支架置入术。该手术在62例患者中的53例取得成功。30例壶腹周围梗阻中有28例能够成功置入，而肝门部26例中只有19例能够成功置入。18例患者出现并发症，但只有3例严重，包括2例与手术相关的死亡。46例计划进行长期引流的患者中，34例胆管梗阻完全缓解，8例部分缓解。40例恶性疾病患者的生存率较低，但6例良性狭窄患者均未死亡。20例长期存活者中有7例，其内置支架最终出现部分或完全堵塞。对于无法切除肿瘤或手术风险高的患者，该技术是缓解瘙痒和黄疸的一种替代方法。对于良性狭窄患者，早期结果令人鼓舞，但需要更长时间的随访来评估这种治疗方法。
