Mann N R, Charuvastra V C, Murthy V K
Int J Addict. 1984 Feb;19(1):25-44. doi: 10.3109/10826088409055815.
The results of analysis of successive relapse and remission times of many opiate addicts were examined. It is discovered that motivation is the preeminent factor that governs the distribution of lengths of remission times (periods of abstinence), differences in types of motivation leading to an underlying mixture of three or fewer Weibull distributions. On the other hand, two distinct factors-namely wear-out (dysfunction resulting from exhaustion or tiring out brought on by the addict's enforced life-style) and precipitation of events that may not be beyond the control of the addict-govern the distribution of lengths of relapse times (periods of using opiates), leading, typically, to an underlying competing-risk distribution. Methods for using this information to aid in treatment and in research are described.
对许多阿片类成瘾者连续复发和缓解时间的分析结果进行了研究。研究发现，动机是决定缓解期（戒毒期）时长分布的首要因素，不同类型的动机差异导致潜在的三种或更少韦布尔分布的混合。另一方面，两个不同的因素——即损耗（由成瘾者强制的生活方式导致的疲惫或耗尽引起的功能障碍）和成瘾者可能无法控制的事件引发——决定了复发期（使用阿片类药物期）时长的分布，通常会导致潜在的竞争风险分布。文中描述了利用这些信息辅助治疗和研究的方法。
