Poole G V, Breyer R H, Holliday R H, Hudspeth A S, Johnston F R, Cordell A R, Mills S A
J Cardiovasc Surg (Torino). 1984 Jan-Feb;25(1):5-11.
A series of 23 cardiac tumors is reported. Six were diagnosed at autopsy; 17 tumors were surgically explored. Eleven of the 17 were myxomas within the left atrium. Eight of the 17 patients presented with congestive heart failure; peripheral and cerebral emboli were also common. The diagnosis was made preoperatively in 10 patients. Two-dimensional echocardiography was the most reliable diagnostic tool. Follow-up averages 55 months; there have been no late deaths or recurrences. The other six surgically treated tumors were: a left ventricular rhabdomyoma, a septal lipoma, a right atrial calcified endocardial mass, a right ventricular fibrosarcoma, a rhabdomyosarcoma, and a sarcoma metastatic to the pericardium and right atrium. From this series and a review of the literature, we concluded that: benign cardiac tumors can usually be excised with a low morbidity and excellent long-term results; malignant cardiac tumors have a dismal prognosis, and operation is primarily diagnostic; tumors metastatic to the heart should be operated upon only if successful palliation seems possible.
报告了一系列23例心脏肿瘤。6例在尸检时确诊;17例肿瘤接受了手术探查。17例中有11例是左心房黏液瘤。17例患者中有8例出现充血性心力衰竭;外周和脑栓塞也很常见。10例患者术前确诊。二维超声心动图是最可靠的诊断工具。随访平均55个月;无晚期死亡或复发。另外6例接受手术治疗的肿瘤分别是:左心室横纹肌瘤、间隔脂肪瘤、右心房钙化心内膜肿物、右心室纤维肉瘤、横纹肌肉瘤以及转移至心包和右心房的肉瘤。根据该系列病例及文献回顾,我们得出结论:良性心脏肿瘤通常可通过手术切除,发病率低且长期效果良好;恶性心脏肿瘤预后不佳,手术主要用于诊断;仅当可能实现成功的姑息治疗时,才应对转移至心脏的肿瘤进行手术。